Diindolylmethane is the substance generated when your body breaks down the indole-3-carbinol, compound that is found in the cruciferous vegetables like kale and broccoli. It is available in the supplement form, and there are a wide range of dim supplements benefits.
Why Many People Take It?
DIM is supposed to produce certain changes in the estrogen metabolism, the biological process that influences development of some hormone dependent cancers like breast cancer. The proponents claim that having diindolylmethane will help to increase the defense against many kinds of the cancer, and promote detoxification as well as support the weight loss.
What are the benefits?
Till now, research on health effects of DIM is highly limited. In the preliminary research, some of the scientists have found dim will influence your body’s metabolism of the estrogen level. Whereas it is thought that altering the estrogen metabolism will help to protect against some hormone-dependent cancers (like breast cancer), there is not enough research that can determine if diindolylmethane will help in the cancer prevention. Here is a look at certain key findings from available studies of use of dim for estrogen reduction:
Even though some of the laboratory studies recommend that diindolylmethane might help to inhibit growth of the breast cancer cells, and there are some clinical studies.
Even though some data also have suggested that using diindolylmethane supplements might slow down the development of the cervical cancer, 2012 study published at British Journal failed to show its benefit.
Other Types of Cancer
The preliminary findings from the test-tube studies & animal-based research also indicate that DIM might offer a little protection against the ovarian cancer, prostate cancer, and colon cancer. But, because of lack of research, it is very soon to tell if diindolylmethane can help to fight such types of cancer in the humans.
Even though DIM supplements are at times touted as the natural weight loss helps, there is not any kind of scientific evidence that can support this claim that using diindolylmethane promotes the weight loss.
Diindolylmethane is made when your body takes indole-3-carbinol, the compound found in following vegetables:
- Brussel sprouts
- Collard greens
- Mustard greens
Diindolylmethane is available in the supplement form, and sold in the natural-food stores & stores that specialize in the dietary supplements.
What are the possible Side Effects?
Till now, not much is actually known about safety of making use of DIM supplements often or in a long term. Because of diindolylmethane’s potential for affecting the estrogen metabolism, there is a little concern that using diindolylmethane supplements can aggravate the hormone sensitive conditions (that includes hormone-dependent cancers, uterine fibroids and endometriosis).
DIM Supplement Caution
DIM isn’t recommended for the pregnant and breastfeeding women, for kids, and for the cancer patients. DIM supplements will possibly worsen the hormone-sensitive conditions (like uterine, breast, and ovarian cancer). It is not recommended for people with the kidney disease.